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Bovine Fibrinogen
Our bovine fibrinogen is available in lyophilized powder. It is manufactured from bovine plasma sourced in the US using our proprietary process.
- Soluble as 4% (w/v) solution in PBS, saline, or distilled water.
- Purity ≥ 95% by SDS-PAGE.
- Stable for up to 2 years as lyophilized powder when stored at or below -20 °C.
Bovine fibrinogen, a plasma glycoprotein that plays a key role in blood coagulation, is produced by the liver in hepatic parenchymal cells. Following activation of the clotting cascade, a complex process involving several enzymes, fibrinogen is cleaved by thrombin to form insoluble fibrin strands that are critical to clot formation and platelet aggregation. Bovine fibrinogen has a molecular weight of 340 kDa and is comprised of α, β, and γ chains connected at their termini by a disulfide knot. Bovine fibrinogen is widely used in haemostasis research, in medicine for haemostatic therapy, in the creation of microporous scaffold matrices for tissue engineering, and in the development of fibrin adhesive products. In mammals, abnormally high or low fibrinogen levels can be an important indicator of inflammation, injury, or disease.
At RMBIO, bovine fibrinogen is purified from fresh bovine plasma using a proprietary process that insures excellent purity, solubility, and long-term stability.
Safe Sourced and Enhanced Manufacturing Processes
Bovine Fibrinogen specific product test requirements and typical values are given below:
| Parameter | Method | Specification |
|---|---|---|
| Appearance | Visual | White to Off-White Powder |
| Chloride | Chemistry Analyzer | As Reported |
| Clottable Protein (%) | Colormetric | ≥ 85% |
| Microbial | Plate Count | As Reported |
| Moisture | Loss on Drying | ≤ 10% |
| pH | pH Meter | 6.0 - 8.0 |
| Potassium | Chemistry Analyzer | As Reported |
| Purity | SDS PAGE | ≥ 90% |
| Sodium | Chemistry Analyzer | As Reported |
| Total Protein | Chemistry Analyzer | 70 -95% |
Certificate of Analysis
Order today and you will receive your Bovine Fibrinogen on the next business day.
Samples
Our products will improve the performance of your science. Our samples will tell you the same thing. Grab some now. Request a sample →Related Products
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