Fetal Bovine Serum (FBS) Heat Inactivated

Fetal Bovine Serum (FBS) Heat Inactivated

RMBIO Fetal Bovine Serum offers full traceability and industry-leading performance and consistency. Heat inactivation helps protect against any growth inhibiting serum complement that may be present.
Catalog Number : FBS-BHT
Purified from validated raw materials of the United States
Size
Price
Quantity
500 ML
$538.88
50 ML
$95.00
 
Catalog Number : FBS-CHT
USDA Approved
Size
Price
Quantity
500 ML
$498.98
50 ML
$85.00
 
Special Order for bulk

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Product Details

RMBIO FBS is sourced from USDA-approved suppliers and is processed in our cGMP-compliant and FDA-registered facility. Our FBS is heat inactivated at 56°C for 30 minutes. RMBIO FBS is processed under strict protocols that ensure sterility, high quality, and excellent growth-promotion and performance over a range of applications and cell lines.

  • Heat inactivated
  • Low endotoxin and hemoglobin levels
  • Average endotoxin level*: < 1 EU/mL (specification = ≤ 10.0 EU/ml)
  • Average hemoglobin level*: < 15 mg/dL (specification = < 30 mg/dL)
  • Total protein: 3.0-4.5 g/dL
  • Triple 0.1 µm sterile filtration
  • 9CFR-tested
  • Excellent growth promotion characteristics
  • Storage conditions: ≤ -10° C

* Data based on last 10 lots produced.

 

Heat Inactivation 101
Heat inactivation is an industry standard treatment that helps protect against growth inhibiting immune factors like serum complement that may be present in the serum. Serum complement can have undesirable impacts on immunological endpoints like detection of neutralizing antibodies, or on the proliferation of viruses. RMBIO manufactures heat inactivated bovine serum by raising the temperature of the serum to 56°C in a water bath and strictly maintaining the condition for 30 minutes.

Heat Inactivated Fetal Bovine Serum (FBS) specific product test requirements and typical values are given below:


Parameter Method Specification
Total Protein Chemistry Analyzer 3.0 - 4.5 g/dL
Osmolality By Osmometer 280 - 360 mOsm/Kg
pH pH Meter 6.5 - 8.5
Hemoglobin USP <90> < 30 mg/dl
Albumin Chemistry Analyzer ≤ 4.5 g/dL
Endotoxin LAL ≤ 10 EU/ml
IgG ELISA As Reported
Sterility, Mycoplasma, and Viral Analysis 9CFR 113.26, 28, 53 Tested
Other Parameters Comprehensive Chemistry Testing As Reported
Heat Inactivation Product is heated at 56°C for 30 minutes to inactivate serum complement
Parameter Method Specification
Total Protein Chemistry Analyzer 3.0 - 4.5 g/dL
Osmolality By Osmometer 280 - 360 mOsm/Kg
pH pH Meter 6.5 - 8.5
Hemoglobin USP <90> < 30 mg/dl
Albumin Chemistry Analyzer ≤ 4.5 g/dL
Endotoxin LAL ≤ 10 EU/ml
IgG ELISA As Reported
Sterility, Mycoplasma, and Viral Analysis 9CFR 113.26, 28, 53 Tested
Other Parameters Comprehensive Chemistry Testing As Reported