Donor Horse Serum - Heat Inactivated Equine Serum
Equine serum can be a cost-effective alternative to fetal bovine serum and can be used as cell culture medium in a variety of applications. RMBIO obtains donor horse serum from closed herds that are carefully controlled and inspected by veterinarians. Horses are regularly tested for equine infectious anemia using Coggins tests. Before collection, donor horses are fasted to ensure lower lipid levels. All lots of equine serum are 0.2µm sterile filtered and feature low hemoglobin levels.
- Heat inactivated at 56°C for 30 minutes
- Sterility, Endotoxin, and Mycoplasma tested
- 9CFR tested
- 0.2µm sterile filtered
- Low hemoglobin levels
- Manufactured at our GMP compliant and FDA registered facility
- Raw material is sourced from audited suppliers offering full traceability
- Custom bottle sizes available upon request
- Storage conditions: ≤ -10° C
Heat Inactivation 101
Heat inactivation is an industry standard treatment that helps protect against growth inhibiting immune factors like serum complement that may be present in the serum. Serum complement can have undesirable impacts on immunological endpoints like detection of neutralizing antibodies, or on the proliferation of viruses. RMBIO manufactures heat inactivated equine serum by raising the temperature of the serum to 56°C in a water bath and strictly maintaining the condition for 30 minutes.
Donor Horse Serum - Equine Serum specific product test requirements and typical values are given below:
|Osmolality||Osmometer||206 - 345 mOsm/Kg|
|pH||pH Meter||6.0 - 8.5|
|Total Protein||Chemistry Analyzer||6.0 - 9.5 g/gL|
|Endotoxin||LAL||≤ 50 EU/mL|
|Mycoplasma||9CFR 113.28||Not Detected|
|Sterility||9CFR 113.26||No Growth|
|Viral Analysis||9CFR 113.53||Not Detected
Product is heated at 56°C for 30 minutes to inactivate serum complement.