Iron Fortified and Gamma Irradiated Calf Serum

Iron Fortified and Gamma Irradiated Calf Serum

RMBIO produces US origin iron supplemented calf serum for use in cell culture media. Supplementing iron to calf serum can enhance serum transferrin levels and can be a much less expensive alternative to FBS. This product is gamma irradiated at an industry standard dose of 25-40kGy.
Catalog Number : CSF-BGF
Purified from validated raw materials of the United States
Size
Price
Quantity
1 L
$140.14
Temporarily out of stock
500 ML
$77.07
Temporarily out of stock
50 ML
$25.00
 
Special Order for bulk

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  • Dialyzed
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Product Details

RMBIO produces US origin iron supplemented calf serum for use in cell culture media. Supplementing iron to calf serum can enhance serum transferrin levels and in many cases be a much less expensive alternative to FBS in promoting cell growth and its effectiveness. The serum is gamma irradiated at an industry standard dose of 25-40kGy. 

  • Sterile 0.2 µm filtered
  • Average endotoxin level*: < 2 EU/ml (specification = ≤ 10.0 EU/ml)
  • Average hemoglobin level*: < 15 mg/dL (specification = < 30 mg/dL)
  • 9CFR tested
  • Gamma irradiated at 25-40kGy
  • For use in diagnostics or as cell culture medium
  • Manufactured at our GMP compliant and FDA registered facility
  • Large volume lot sizes available
  • Packaged in 500mL and 1L bottles. Custom container sizes available
  • Storage conditions: ≤ -10° C

*Data based on last 10 lots produced.

 

Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:

  • No potential for residual contaminants
  • Widely accepted by pharmaceutical and research industries
  • Accepted by regulatory agencies
  • Minimal effect on product performance
  • Effective virus inactivation

Parameter Method Specification
Hemoglobin SUP<90> < 30 mg/dL
Osmolality Osmometer 240 - 340 mOsm/Kg
pH pH Meter 7.0 - 7.9
Total Protein Chemistry Analyzer 5.0 - 8.0 g/gL
Endotoxin LAL ≤ 10.0 EU/ml
Mycoplasma 9CFR 113.28 Not Detected
Sterility 9CFR 113.26 No Growth
Viral Analysis 9CFR 113.53 Not Detected
Gamma Irradiated 25-40 kGy