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Fetal Bovine Serum (FBS) Gamma Irradiated

Fetal Bovine Serum (FBS) Gamma Irradiated

RMBIO FBS is sourced from USDA audited suppliers within the United States and offers full traceability, as well as industry-leading performance and consistency. Our FBS is then gamma irradiated at an industry standard dose of 25-40kGy.
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Catalog Number : FBS-BTG
Purified from validated raw materials of the United States
50 ML
Special Order for bulk

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Product Details

RMBIO FBS is sourced from USDA-approved suppliers and is processed in our cGMP-compliant and FDA-registered facility. RMBIO FBS is processed under strict protocols that ensure sterility, high quality, and excellent growth-promotion and performance over a range of applications and cell lines.

  • Low endotoxin and hemoglobin levels
  • Excellent growth promotion characteristics
  • Average endotoxin level*: < 1 EU/mL (specification = ≤ 10.0 EU/ml)
  • Average hemoglobin level*: < 15 mg/dL (specification = < 30 mg/dL)
  • Total protein: 3.0-4.5 g/dL
  • Triple 0.1 µm sterile filtration
  • 9CFR-tested
  • US origin
  • Storage conditions: ≤ -10° C
  • Gamma irradiation 25-40kGy

*Data based on last 10 lots produced.

Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:
No potential for residual contaminants

  • Widely accepted by pharmaceutical and research industries
  • Accepted by regulatory agencies
  • Minimal effect on product performance
  • Effective virus inactivation

Gamma Irradiated Fetal Bovine Serum (FBS) specific product test requirements and typical values are given below:

Parameter Method Specification
Total Protein Colorimetric Assay 3.0 - 4.5 g/dL
Osmolality By Osmometer 280 - 340 mOsm/Kg
pH pH Meter 7.0 - 8.0
Hemoglobin Contract Lab < 25 mg/dl
Albumin Contract Lab 1.7 - 3.4 g/dL
Endotoxin LAL < 10 EU/ml
IgG ELISA As Reported
Electrophoretic ID Gel Electrophoresis Characteristic
Other Parameters Comprehensive Chemistry Testing As Reported
Gamma Irradiation 25-40kGy

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