RMBIO produces high quality, low hemoglobin, US sourced calf serum for use in diagnostics and cell culture media. Bovine calf serum provides the start for successful cell growth at a fraction of the price of Fetal Bovine Serum due to its availability. Our calf serum is then irradiated at an industry standard dose of 25-40kGy.

• Average endotoxin level*: < 2 EU/ml (specification = ≤ 10.0 EU/ml)
• Average hemoglobin level*: < 15 mg/dL (specification = < 30 mg/dL)
• 9CFR tested
• Sterile 0.2 µm filtered
• Gamma irradiated at 25-40kGy
• Manufactured at our GMP compliant and FDA registered facility
• Packaged in 500mL and 1L bottles. Custom container sizes available upon request.
• Storage conditions: ≤ -10° C

*Data based on last 10 lots produced.

Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:

• No potential for residual contaminants
• Widely accepted by pharmaceutical and research industries
• Accepted by regulatory agencies
• Minimal effect on product performance
• Effective virus inactivation