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Gamma irradiated Fetal Bovine Serum in a transparent 500 milliliter bottle.

Fetal Bovine Serum (FBS) Gamma Irradiated

RMBIO FBS is sourced from USDA audited suppliers within the United States and offers full traceability, as well as industry-leading performance and consistency. Our FBS is then gamma irradiated at an industry standard dose of 25-40kGy.
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Catalog Number : FBS-BTG
Purified from validated raw materials of the United States
50 ML
Special Order for bulk

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Product Details

RMBIO FBS is sourced from USDA-approved suppliers and is processed in our cGMP-compliant and FDA-registered facility. RMBIO FBS is processed under strict protocols that ensure sterility, high quality, and excellent growth-promotion and performance over a range of applications and cell lines.

  • Low endotoxin and hemoglobin levels
  • Excellent growth promotion characteristics
  • Average endotoxin level*: < 1 EU/mL (specification = ≤ 10.0 EU/ml)
  • Average hemoglobin level*: < 15 mg/dL (specification = < 30 mg/dL)
  • Total protein: 3.0-4.5 g/dL
  • Triple 0.1 µm sterile filtration
  • 9CFR-tested
  • US origin
  • Storage conditions: ≤ -10° C
  • Gamma irradiation 25-40kGy

*Data based on last 10 lots produced.

Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:
No potential for residual contaminants

  • Widely accepted by pharmaceutical and research industries
  • Accepted by regulatory agencies
  • Minimal effect on product performance
  • Effective virus inactivation

Gamma Irradiated Fetal Bovine Serum (FBS) specific product test requirements and typical values are given below:

Parameter Method Specification
Total Protein Colorimetric Assay 3.0 - 4.5 g/dL
Osmolality By Osmometer 280 - 340 mOsm/Kg
pH pH Meter 7.0 - 8.0
Hemoglobin Contract Lab < 25 mg/dl
Albumin Contract Lab 1.7 - 3.4 g/dL
Endotoxin LAL < 10 EU/ml
IgG ELISA As Reported
Electrophoretic ID Gel Electrophoresis Characteristic
Other Parameters Comprehensive Chemistry Testing As Reported
Gamma Irradiation 25-40kGy

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