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Gamma irradiated and heat inactivated Porcine Serum in a transparent 1000 milliliter bottle.

Pig Serum - Porcine Serum, Gamma Irradiated and Heat Inactivated

RMBIO sources porcine serum from US farms. Pig serum is ideal for vaccine production and cell culture applications. Our most popular treatments for RMBIO porcine serum are gamma irradiation and heat inactivation. Heat inactivation helps protect against growth inhibiting serum complement while gamma irradiation helps achieve pathogen reduction.
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Catalog Number : PSF-BHG
Purified from validated raw materials of the United States
1 L
Special Order for bulk

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Product Details

RMBIO porcine serum is ideal for use as a cell culture media especially in vaccine production. We carefully control the entire production process. Our pig serum is 0.2µm sterile filtered and features low hemoglobin levels. The serum is then heat inactivated at 56°C for 30 minutes before being gamma irradiated at an industry standard dose of 25-40kGY.

  • Material obtained from adult animals
  • Sterility, endotoxin, and Mycoplasma tested
  • 9CFR tested
  • Heat inactivated
  • Gamma irradiated
  • Low hemoglobin levels
  • Packaged in 1L bottles. Custom packaging sizes available.
  • US origin
  • Storage conditions: ≤ -10° C

Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:

  • No potential for residual contaminants
  • Widely accepted by pharmaceutical and research industries
  • Accepted by regulatory agencies
  • Minimal effect on product performance
  • Effective virus inactivation

Heat Inactivation 101
Heat inactivation is an industry standard treatment that helps protect against growth inhibiting immune factors like serum complement that may be present in the serum. Serum complement can have undesirable impacts on immunological endpoints like detection of neutralizing antibodies, or on the proliferation of viruses. RMBIO manufactures heat inactivated bovine calf serum by raising the temperature of the serum to 56°C in a water bath and strictly maintaining the condition for 30 minutes.

Pig Serum - Porcine Serum, Gamma Irradiated and Heat Inactivated specific product test requirements and typical values are given below:

Parameter Method Specification
Total Protein Chemistry Analyzer 6.0 - 9.5 g/dL
Osmolality By Osmometer 206 - 345 mOsm/Kg
pH pH Meter 6.5 - 8.5
Endotoxin LAL As Reported
Sterility 9CFR 113.26 No Growth
Mycoplasma 9CFR 113.28 Not Detected
Hemoglobin Spec. Assay As Reported
Viral Analysis 9CFR 113.53 Not Detected
Appearance Visual Clear Amber Solution
Gamma Irradiated 25-40kGy
Heat Inactivation Product is heated at 56°C for 30 minutes to inactivate serum complement,

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