Pig Serum - Porcine Serum, Gamma Irradiated and Heat Inactivated
RMBIO porcine serum is ideal for use as a cell culture media especially in vaccine production. We carefully control the entire production process. Our pig serum is 0.2µm sterile filtered and features low hemoglobin levels. The serum is then heat inactivated at 56°C for 30 minutes before being gamma irradiated at an industry standard dose of 25-40kGY.
- Material obtained from adult animals
- Sterility, endotoxin, and Mycoplasma tested
- 9CFR tested
- Heat inactivated
- Gamma irradiated
- Low hemoglobin levels
- Packaged in 1L bottles. Custom packaging sizes available.
- US origin
- Storage conditions: ≤ -10° C
Gamma Irradiation 101
Gamma irradiation is a physical inactivation approach used to achieve pathogen reduction in the serum. This mitigates risk from low-level contaminants that may not be detected through viral or mycoplasma testing. RMBIO serum is gamma irradiated via controlled exposure to Cobalt 60 at an industry standard dose of 25-40kGy. Most typical viral contaminants of bovine serum are readily inactivated at this irradiation range. Advantages of gamma irradiation include:
- No potential for residual contaminants
- Widely accepted by pharmaceutical and research industries
- Accepted by regulatory agencies
- Minimal effect on product performance
- Effective virus inactivation
Heat Inactivation 101
Heat inactivation is an industry standard treatment that helps protect against growth inhibiting immune factors like serum complement that may be present in the serum. Serum complement can have undesirable impacts on immunological endpoints like detection of neutralizing antibodies, or on the proliferation of viruses. RMBIO manufactures heat inactivated bovine calf serum by raising the temperature of the serum to 56°C in a water bath and strictly maintaining the condition for 30 minutes.
|6.0 - 9.5 g/dL
|206 - 345 mOsm/Kg
|6.5 - 8.5
|Clear Amber Solution
|Product is heated at 56°C for 30 minutes to inactivate serum complement,
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